Classic symptoms of hyperglycemia usually include which trio?

• A. Polyuria, polyphagia, and weight loss
• B. Polyuria, polydipsia, and polyphagia
• C. Weight gain and fatigue
• D. Nausea and vomiting

Answer: (B)

When blood glucose runs high, the kidneys can’t reabsorb it all, so glucose spills into the urine and pulls extra water with it—this osmotic diuresis produces polyuria. The resulting dehydration triggers increased thirst, or polydipsia. At the same time, even though glucose is high in the blood, many cells can’t take it up effectively, signaling the body to increase hunger, or polyphagia. Taken together, these three symptoms—polyuria, polydipsia, and polyphagia—are the classic trio seen with hyperglycemia. The other options either omit one of these core signs or describe symptoms that are less characteristic of the typical hyperglycemic presentation.