How can you clinically and laboratorily differentiate diabetic nephropathy from hypertensive nephrosclerosis?

• A. Retinopathy is more common with hypertensive nephrosclerosis.
• B. Diabetic nephropathy often coexists with retinopathy and progressive albuminuria; hypertensive nephrosclerosis shows CKD with long-standing hypertension and less pronounced albuminuria.
• C. Hypertensive nephrosclerosis shows rapid onset of heavy proteinuria.
• D. Imaging alone can definitively differentiate the two conditions.

Answer: (B)