What is the significance of thyroid-stimulating immunoglobulins in neonatal thyrotoxicosis and infants of mothers with Graves' disease?

• A. Thyroid-stimulating immunoglobulins cross the placenta and can cause neonatal hyperthyroidism; monitor newborns and treat if present.
• B. Thyroid-stimulating immunoglobulins have no role in neonatal thyroid disease.
• C. TSIs decrease neonatal thyroid activity, preventing thyrotoxicosis.
• D. TSIs only affect the mother and do not cross the placenta.

Answer: (A)