Which of the following is a psychological symptom that can occur in hypothyroidism?

• A. Euphoria
• B. Apathy
• C. Anxiety
• D. Mania

Answer: (B)

Hypothyroidism can produce neuropsychiatric changes, including slowed thinking, fatigue, and reduced motivation. Apathy fits this pattern because it describes a diminished interest and emotional responsiveness, mirroring the overall sluggish, low-energy state typical of hypothyroidism. Euphoria and mania reflect elevated or unusually expansive mood states, which are not characteristic of hypothyroid physiology and are more associated with conditions like bipolar disorder or thyrotoxic states. Anxiety is more commonly linked to hyperthyroidism or primary anxiety disorders rather than the depressive-like, motivationally blunted picture seen with hypothyroidism. Thus, apathy is the most appropriate psychological symptom associated with hypothyroidism.